ABSTRACT
1,2,3-triazole is a five-member nitrogen-containing heterocyclic compound with diverse biological activities. A number of 1,2,3-triazole-containing FDA-approved drugs are available on the market, and many other pharmaceutically significant potential molecules are under clinical investigation. Therefore, it is fairly reasonable to anticipate that there will be an increase in demand for new triazole-containing drugs in the coming future. Because of its broad pharmacological applications, it has recently attracted the attention of scientists worldwide. This review provides a concise summary of the synthetic techniques for triazole compounds from various strategies and their medical importance as a lead structure for the enhancement of therapeutic molecules.
Acknowledgement
The authors extend their appreciation to the Deanship of Scientific Research at King Khalid University, Saudi Arabia, for funding this work through the Large Program (grant number RGP-2/374/44). The authors are thankful to the Department of Chemistry, Marwadi University, Rajkot, Gujarat, India.
Author’s contribution
Conceptualization, M.J.V., M.R., S.B. and V.J.; methodology, V.J., S.B. and M.J.V.; software, L.B., M.R. and K.Y.T.; writing-original draft preparation, M.J.V., S.B. and V.J.; writing – review and editing, M.R., M.M.A., S.A.F. and I.P.; supervision, L.B., and I.P.; funding acquisition, K.Y.T. All authors have read and agreed to the published version of the manuscript.
Disclosure statement
No potential conflict of interest was reported by the author(s).