From a hunger-regulating hormone to an antimicrobial peptide: gastrointestinal derived circulating endocrine hormone-peptide YY exerts exocrine antimicrobial effects against selective gut microbiota

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Disclosure statement

No potential conflict of interest was reported by the author(s).

Authors’ contributions

Y.X. and C.Z. wrote the main text and prepared figures. L.J. supervised the study. C.Z. designed the study, administered the grant, and approved the final manuscript.

Data availability statement

All of the data generated from this article are all included in this manuscript.

Additional information

Funding

This study was supported by the National Key Research and Development Program (Grant No. 2023YFC3604500), National Natural Science Foundation of China (Grant No. 32271165, 82172545, 82230084) and the Interdisciplinary Project in Ocean Research of Tongji University (Grant No. 2022-2-ZD-02).