ADM-assisted prepectoral breast reconstruction is not associated with high complication rate as before: a Meta-analysis

Abstract

Implant-related breast reconstruction can be divided into subpectoral breast reconstruction (SPBR) and prepectoral breast reconstruction (PPBR) according to the different anatomical planes. The previous stereotype was that PPBR had a high complication rate and was not suitable for clinical use. However, with the emergence of acellular dermal matrix (ADM), the clinical effect of PPBR has been improved. To compare the outcomes difference between SPBR and PPBR, We conducted this meta-analysis. Articles on SPBR versus PPBR were searched in PubMed, Web of Sciences, Embase, and Cochrane databases, strictly following the PRISMA guidelines. According to the set criteria, we included the literature that met the requirements. Extracted data were the incidence of adverse events and the duration of drainage. Results show that SPBR has a higher incidence rate in capsular contracture, animation deformity, infection, hematoma and delayed healing wound than PPBR. There are no significant differences in skin flap necrosis, seroma, implant loss, reoperation and duration of drainage between the two groups. Hence, PPBR is no longer a high complication surgical method and can be used in the clinical practice. However, there are few large sample studies at present, so it is necessary to carry out further studies on PPBR.

Keywords:

• Prepectoral
• submuscular
• breast reconstruction
• implant

Author contributions

Jiaheng Xie, Yuan Cao, Shujie Ruan, Mengmeng Ou, Pan Yu: acquisition of data, analyzing and interpretation of data, drafting the article; Jingping Shi, Zhechen Zhu, Ming Wang,: designing, revising, and guiding the study. The authors read and approved the final manuscript.

Disclosure statement

The authors declare that they have no competing interests.

Data availability statement

All the data for this article can be found on Pubmed.