Clinical assessment of breast symmetry and aesthetic outcome: can 3D imaging be the gold standard?

Abstract

There is a lack of an accurate standardised objective method to assess aesthetic outcome after breast surgery. In this methodological study, we investigated the intra- and inter-observer reproducibility of breast symmetry and volume assessed using three-dimensional surface imaging (3D-SI), evaluated the reproducibility depending on imaging posture, and proposed a new combined volume-shape-symmetry ($\mathit{VSS}$) parameter. Images were acquired using the VECTRA XT 3D imaging system, and analysed by two observers using VECTRA Analysis Module. Breast symmetry was measured through the root mean square distance. All women had undergone bilateral risk-reducing mastectomy and immediate breast reconstruction. The reproducibility and correlations of breast symmetry and volume measurements were compared using Bland–Altman’s plots and tested with Spearman’s rank correlation coefficient. 3D surface images of 58 women were analysed (348 symmetry measurements, 696 volume measurements). The intra-observer reproducibility of breast symmetry measurements was substantial–excellent, the inter-observer reproducibility was substantial, and the inter-posture reproducibility was substantial. For measurements of breast volumes, the intra-observer reproducibility was excellent, the inter-observer reproducibility was moderate–substantial, and the inter-posture reproducibility was substantial–excellent. The intra-observer reproducibility of $\mathit{VSS}$ was excellent while the inter-observer reproducibility was substantial for both observers, independent of posture. There were no statistically strong correlations between breast symmetry and volume differences. The intra-observer reproducibility was found to be substantial–excellent for several 3D-SI measurements independent of imaging posture. However, the inter-observer reproducibility was lower than the intra-observer reproducibility, indicating that 3D-SI in its present form is not a great assessment for symmetry.

Keywords:

• Three-dimensional surface imaging
• stereophotogrammetry
• aesthetic outcome
• breast symmetry
• breast volume
• imaging posture
• reproducibility

Acknowledgements

The authors would like to thank the participating women, and Vivianne Lindbergh and Maria Norberg Barkman, Department of Medical Imaging, Karolinska University Hospital. Associate Professor Elisabeth Elder, Westmead Breast Cancer Institute, University of Sydney.

Disclosure statement

The authors declare that they have no competing interests.

Notes

1 The lasso tool is useful for drawing freehand boarders to select or de-select an area of an image. It works similarly as in Adobe Photoshop or Illustrator.

Additional information

Funding

This study was funded by the Swedish Cancer Society, Swedish Research Council, Radiumhemmets forskningsfonder, and the Breast Cancer Foundation Research Fund.