https://orcid.org/0000-0001-5570-9226
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ABSTRACT
Objective
to compare the results of using Dapoxetine and HA (hyaluronic acid) gel injection by Five puncture technique in the treatment of premature ejaculation (PE).
Methods
100 sexually active heterosexuals circumcised males with lifelong PE were included in the study. Group A patients were treated with on-demand Dapoxetine, while group B was treated with HA gel glans penis injection using a five-puncture technique. Both groups were evaluated at 1st,3rd and 6th months post-treatment using IELT.
Results
There were no significant differences between both groups regarding patient demographic. Mean pretreatment IELT in groups A and B were 45.82 ± 7.44 and 46.18 ± 7.82 receptively. There was no significant difference between both groups. After treatment, both groups show significant ILET improvement during the 1st,3rd, and 6th months follow-up with a P value < 0.001. However, when comparing the improvement of ILET in group A (Dapoxetine) and group B (HA injection), there were high significance differences in favor of group B in the 1st,3rd, and 6th-month follow-up.
Conclusion
Although both treatment modalities have improved IELT and premature ejaculation, but HA injection with five punctures technique was significantly better than oral Dapoxetine with self-limited side effects.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Authors contributions
Ibrahim M. Ibrahim: Protocol development and Manuscript writing.
Moustafa Mohamed: Manuscript writing and Data analysis.
Mostafa Kamel: Data collection.
Lotfy Elbendary: Data analysis
Almaqtouf Mohamed: Protocol development and Data analysis
S Elderey Mohamed: Protocol development, Data collection, and Manuscript writing.