Structural basis of poxvirus A16/G9 binding for sub-complex formation

Click to increase image sizeClick to decrease image size

Acknowledgements

We thank the staffs from BL19U1 beamline of National Facility for Protein Science in Shanghai (NFPS) at Shanghai Synchrotron Radiation Facility, for assistance during data collection. Author Contributions: G.L. conceived the study and supervised the whole project. F.Y. and S.L. conducted the majority of the experiments. F.Y., Z.C. and D.Y. collected the datasets and solved the structure. D.Y. and M.Y. assisted with the protein preparation. G.L., F.Y. and S.L. wrote the manuscript. B.H., Y.C., H.D., J.L. and Q.Z. provided the reagents and participated in experimental design as well as manuscript editing and discussion.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability

The datasets used and/or analysed during this study are available from the corresponding author on reasonable request. Atomic coordinates and structure factors for the reported crystal structure has been deposited into the Protein Data Bank under accession number 8GP6.

Additional information

Funding

This work was supported by the National Natural Science Foundation of China [grant number 81971925] and the 1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University [grant number ZYYC20008].