Metastatic salivary gland mammary analogue secretory carcinoma (MASC) of parotid gland – A rare case report in the literature review

Abstract

We present a patient diagnosed with a parotid tumor whose histopathology was MASC. A 58-year-old female presented with a 5-month history of an enlarging right parotid mass. Ultrasonography showed a 48 × 30 mm heterogeneous solid lesion with a lobulated contour in the right parotid gland. A neck computed tomography (CT) with intravenous (IV) contrast showed a 28 × 34 mm pathological mass in the right parotid gland. After FNA, parotidectomy, and modified radical neck dissection, pathology showed that the surgical margin was positive for tumor, and one lymph node was metastatic in the right neck. This case was classified as T2N1M1 staged MASC of the salivary gland. She completed seven weeks of radiation therapy (RT) after surgery, and no recurrence or metastasis was observed at the 32nd-month follow-up. We aimed to report a rare parotid gland tumor with this case and inspire new research on diagnosing and treating rare salivary gland tumors

Keywords:

• Cancer
• mammary analog secretory carcinoma
• MASC
• parotid
• salivary gland carcinoma

Acknowledgments

We would like to acknowledge the team at the Izmır Bozyaka Education and Research Hospital for their support in the care of this patient.

Informed consent

The patient consented to the publication of this case report.

Authors’ contributions

A.A.: Study design, examination of patients, data collection and analysis, manuscript development, and review of the final manuscript. T.M.: Study design, examination of patients, data collection and analysis, manuscript development, review of the final manuscript. Z.K.: Study design, data collection, and analysis, manuscript development, review of the final manuscript.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

Data sharing does not apply to this article as no datasets were generated or analyzed during the current study.