ABSTRACT
In past years, various studies have considered transdermal drug delivery system for improving patient compliance. One approach to deliver drug via transdermal route is transdermal patch. These patches include single-layer drug in adhesive patches and micro reservoir transdermal patch & matrix system. Acrylic-acid, hydroxypropyl methylcellulose (HPMC) and polyethylene glycol are commonly used polymers for manufacturing of transdermal patches. Characterization of patches includes patch thickness, weight uniformity, irritation studies, in-vitro drug release and permeation studies. This review summarizes various polymers, types of transdermal patches and evaluation of transdermal patches based on up-to-date data extracted from reputed journals and official websites.
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Ansa Ashfaq
Ansa Ashfaq, She is a Researcher in Faculty of Pharmaceutical Sciences, University of Central Punjab, Lahore, Pakistan.
Tehseen Riaz
Tehseen Riaz, She is a Senior Lecturer in Faculty of Pharmaceutical Sciences, University of Central Punjab, Lahore, Pakistan.
Muhammad Ahsan Waqar
Muhammad Ahsan Waqar, He is a Lecturer in Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Lahore University of Biological & Applied Sciences, Lahore, Pakistan.
Muhammad Zaman
Muhammad Zaman, He is an Associate Professor in Faculty of Pharmaceutical Sciences, University of Central Punjab, Lahore, Pakistan.
Imtiaz Majeed
Imtiaz Majeed, He is an Associate Professor in Faculty of Pharmaceutical Sciences, University of Central Punjab, Lahore, Pakistan.