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Original Article

Two New Minor Compounds with Inhibitory Effect on K562 Cells from Ventilago leiocarpa Benth

, , , , , & show all
Pages 35-41 | Received 28 Jan 2000, Accepted 09 May 2000, Published online: 20 Aug 2009
 

Abstract

Two new minor compounds, 1,6-dihydroxy-3-methyl-xanthone-8-acid-1-O-ß-D-glucopyranoside (1) and 1,6-dihydroxy-3-methyl-xanthone-8-acid-1-O-ß-D-glucopyranosyl (1 6) ß-D-glucopyra-noside (2) isolated from Ventilago leiocarpa Benth., have been assessed for inhibitory effect on the growth of human cancer cell line K562 in vitro by colorimetric assay utilizing methyl thiazolyl tetrazolium (MTT). Their structures were elucidated on the basis of chemical and spectroscopic evidences (IR, UV, MS, 1H-NMR, 13C-NMR, 13C-1HCOSY and HMBC).

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