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Original Article

Detection and Determination of Chemical Groups in an Extract of Allophylus cominia(L.)

(Master in Pharmacology) , (Master in Technology and Medicinal Control) , (PhD in Veterinarian Sciences) , (PhD in Veterinarian Sciences) & (PhD in Veterinarian Sciences)
Pages 31-38 | Published online: 24 Aug 2009
 

Abstract

The preliminary chemical characterization of the aqueous extract of Allophylus cominia(L.) Swleaves was carried out by a phytochemical screening, the determination of the protein concentration by Lowry’s method, as well as the composition of fatty acids and carbohydrates by gaseous chromatography (GC). The presence of the free amine groups, free phenolics, tannins, leucoantocianidines, saponines, triterpens, and steroids was detected. The concentration of proteins were 6.22 mg/mL. The composition of fatty acids (%) were: lauric acid (C12): 1.87; miristic acid (C14): 9.13; palmitic acid (C16): 19.87; stearic acid (C18): 8.35; and araquidic acid (C20): 7.83. The identified carbohydrates (mg/mg totals) were: arabinose: 0.06; xilose: 0.025; galactose: 0.241; and glucose: 1.2. Some members of these analyzed groups are reported in literature as potent hypoglycemic agents. For this reason, the presence of these substances in the analyzed extract may be one of the factors that contribute to the pharmacological effect of their administration in experimental diabetic models.

Additional information

Notes on contributors

Tania Véliz Rodríguez

F. U. Alakbarov is Head Scientific Officer, expert in the Oriental and Folk Medicine, Institute of Manuscripts of the Azerbaijan Academy of Sciences, 8 Istiglaliyat str., Baku, 370001, Azerbaijan.

At the time of writing Liya Davydov was PharmD candidate, College of Pharmacy and Allied Health Professions, St. John’s University. Currently, she is Pharmacy Practice Resident, Mount Sinai Medical Center, New York, NY.

Ila Mehra Harris is Assistant Professor, Department of Pharmaceutical Care & Health Systems, College of Pharmacy, and Clinical Assistant Professor, Department of Family Practice & Community Health, Medical School, University of Minnesota, Minneapolis, MN.

Colin J. Briggs is Professor of Pharmacy, Faculty of Pharmacy, University of Manitoba. Recently he completed a secondment to Health Canada, as Senior Science Advisor in the Therapeutics Products Programme with special responsibility for complementary medicines.

Gemma Briggs is Research Assistant, IMPACT, The Injury Prevention Centre of Children’s Hospital, 501G-715 John Buhler Research Centre, Winnipeg, MB, Canada.

Mary Chavezis Professor of Pharmacy Practice, Director of Complementary Medicine Education and Research, The Center for the Advancement of Pharmacy Practice, Midwestern University, College of Pharmacy Glendale, Glendale, AZ 85308.

June Riedlinger was Director of the Center for Integrative Therapies in Pharmaceutical Care, Massachusetts College of Pharmacy and Health Sciences, Boston, MA. Currently he is Adjunct Associate Professor of Neuropathic Medicine, Southwest College of Naturopathic Medicine & Health Sciences, 2140 East Broadway Road, Tempe, AZ 85282.

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