Abstract
Adhatoda vasica Nees (Acantheceae), commonly known as Vasaka, is a well-known plant in indigenous systems of medicine and is used for its beneficial effects, particularly in bronchitis. The present investigation was carried out to study the antiulcer activity of Adhatoda vasica leaves using two ulcer models (1) Ethanol-induced, and (2) Pylorus ligation plus aspirin-induced models. Adhatoda vasica leaf powder showeda considerable degree of antiulcer activity in experimental rats when compared with a control. The highest degree of activity (80%) was observed in the ethanol-induced ulceration model. Results of the study suggest that in addition to its classically established pharmacological activities, the plant also has immense potential as an antiulcer agent of great therapeutic relevance.
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Notes on contributors
N. Shrivastava
F. U. Alakbarov is Head Scientific Officer, expert in the Oriental and Folk Medicine, Institute of Manuscripts of the Azerbaijan Academy of Sciences, 8 Istiglaliyat str., Baku, 370001, Azerbaijan.
At the time of writing Liya Davydov was PharmD candidate, College of Pharmacy and Allied Health Professions, St. John’s University. Currently, she is Pharmacy Practice Resident, Mount Sinai Medical Center, New York, NY.
Ila Mehra Harris is Assistant Professor, Department of Pharmaceutical Care & Health Systems, College of Pharmacy, and Clinical Assistant Professor, Department of Family Practice & Community Health, Medical School, University of Minnesota, Minneapolis, MN.
Colin J. Briggs is Professor of Pharmacy, Faculty of Pharmacy, University of Manitoba. Recently he completed a secondment to Health Canada, as Senior Science Advisor in the Therapeutics Products Programme with special responsibility for complementary medicines.
Gemma Briggs is Research Assistant, IMPACT, The Injury Prevention Centre of Children’s Hospital, 501G-715 John Buhler Research Centre, Winnipeg, MB, Canada.
Mary Chavezis Professor of Pharmacy Practice, Director of Complementary Medicine Education and Research, The Center for the Advancement of Pharmacy Practice, Midwestern University, College of Pharmacy Glendale, Glendale, AZ 85308.
June Riedlinger was Director of the Center for Integrative Therapies in Pharmaceutical Care, Massachusetts College of Pharmacy and Health Sciences, Boston, MA. Currently he is Adjunct Associate Professor of Neuropathic Medicine, Southwest College of Naturopathic Medicine & Health Sciences, 2140 East Broadway Road, Tempe, AZ 85282.
Gauri Madhav Chauhan and Suresh R. Naik belong to Principal K.M. Kundanani College of Pharmacy affiliated with Mumbai University, Mumbai, India.