Abstract
Eighty-seven patients with toenail onychomycosis were treated with intermittent low-dose itraconazole, 200 mg day-1 for one week every four weeks; this regimen was repeated six times. A total of 77 patients (88·5%) showed microscopical and cultural cure after 6 months of treatment. A three-year follow-up showed a relapse rate of 6·5% occurring only during the first year after treatment.