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Chronobiology International
The Journal of Biological and Medical Rhythm Research
Volume 18, 2001 - Issue 2
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Original

AN UNDERLYING CIRCANNUAL RHYTHM IN SEASONAL AFFECTIVE DISORDER?

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Pages 309-313 | Received 24 Jul 2000, Accepted 19 Sep 2000, Published online: 07 Jul 2009
 

Abstract

A patient diagnosed with seasonal affective disorder (SAD) carried out prospective ratings of depression weekly for nearly a decade. A winter peak of depression and benzodiazepine intake was documented. However, over the years, the depressive episodes shifted toward spring in an apparent free-running circannual rhythm (periodogram peaks at 53 and 55 weeks). This patient may have an underlying seasonal propensity to depression no longer precisely entrained to environmental cues. (Chronobiology International, 18(2), 309–313, 2001)

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