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Synthetic Communications

An International Journal for Rapid Communication of Synthetic Organic Chemistry

Volume 31, 2001 - Issue 3

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Original Articles

UNPRECEDENTED SYNTHESIS OF HANTZSCH 1,4-DIHYDROPYRIDINES UNDER BIGINELLI REACTION CONDITIONS^*

Jhillu S. Yadav Organic Division-I, Indian Institute of Chemical Technology, Hyderabad, 500 007, India

,

Basi V. Subba Reddy Organic Division-I, Indian Institute of Chemical Technology, Hyderabad, 500 007, India

&

Polepally Thirupathi Reddy Organic Division-I, Indian Institute of Chemical Technology, Hyderabad, 500 007, India

Abstract

Hantzsch 1,4-dihydropyridines are synthesized in high yields by a one-pot cyclocondensation of aldehyde, β-ketoester, and urea on the surface of silica gel under microwave irradiation in solvent-free conditions.

ACKNOWLEDGMENT

BVS and PTK thank CSIR, New Delhi, for the award of fellowship.

Notes

^*IICT Communication No. 4425.

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