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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 6
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Original Articles

SOLID-PHASE SYNTHESIS OF 2,4,6-TRIAMINOPYRIMIDINES

Kyung Ho Yoo Medicinal Chemistry Research Center, Korea Institute of Science and Technology, Seoul, 130-650, Korea
,
Sung Eun Kim Medicinal Chemistry Research Center, Korea Institute of Science and Technology, Seoul, 130-650, Korea
,
Kye Jung Shin Medicinal Chemistry Research Center, Korea Institute of Science and Technology, Seoul, 130-650, Korea
,
Dong Chan Kim Medicinal Chemistry Research Center, Korea Institute of Science and Technology, Seoul, 130-650, Korea
,
Sang Woo Park Medicinal Chemistry Research Center, Korea Institute of Science and Technology, Seoul, 130-650, Korea
&
Dong Jin Kim Medicinal Chemistry Research Center, Korea Institute of Science and Technology, Seoul, 130-650, Korea
Pages 835-840 | Received 27 Mar 2000, Published online: 09 Nov 2006
 
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Abstract

A novel method for polymer-supported synthesis of 2,4,6-triaminopyrimidines 1a–h on the basis of sequential nucleophilic substitution of appropriate amines to pyrimidine template is described.

ACKNOWLEDGMENTS

This work was supported by a research grant from Korea Institute of Science and Technology.

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