DIRECTED ORTHO LITHIATION OF N-TERT-BUTYLBENZENESULFINAMIDE

Abstract

Introducing the sulfinamide group as a new useful ortho-directing group, we are presenting the synthesis of a series of ortho-substituted N-tert-butylbenzenesulfinamides via directed lithiation of the title compound and subsequent quenching of the dilithiated intermediates with various electrophiles.

Acknowledgments