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Abstract
Treatment of L-cysteine esters and thiazolidine-4-carboxylic esters with an excess of paraformaldehyde in the presence of trifluoroacetic acid provides C 2-symmetric N,N′-methylenebisthiazolidines in good yield.
ACKNOWLEDGMENTS
We thank Dr. Jaume Granell for many helpful discussions and suggestions and Dr. David Amabilino for constructive criticism of the manuscript. Support for this research was provided by DGICYT through Grant PB97-0877 and UB-FEDER 2FD97-0293.