SYNTHESIS OF SOME AMINO ACID ESTER LINKED DIOXATHIAPHOSPHOCIN/DIOXAPHOSPHOCIN DERIVATIVES

L. Nagaprasada Rao Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, India

C. Devendranath Reddy Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, India

V. Krishna Reddy Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, India

K. Ananda Kumar Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, India

C. Suresh Reddy Department of Chemistry, Sri Venkateswara University, Tirupati, 517 502, India

Abstract

Novel 6/8-amido(methoxyglycinyl/alaninyl)dioxathiaphosphocins/dioxaphosphocins (4, 7, 10) have been synthesized from reactions of monochlorides (3,6,9) with glycine methyl ester or alanine methyl ester hydrochlorides (1a,b) at room temperature in dry tetrahydrofuran in the presence of triethylamine.

ACKNOWLEDGMENTS

The authors express their thanks to Directors SIF, IISc Bangalore and CDRI, Lucknow, for spectral recording. L. N. Rao is thankful to UGC for awarding a fellowship.

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SYNTHESIS OF SOME AMINO ACID ESTER LINKED DIOXATHIAPHOSPHOCIN/DIOXAPHOSPHOCIN DERIVATIVES

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SYNTHESIS OF SOME AMINO ACID ESTER LINKED DIOXATHIAPHOSPHOCIN/DIOXAPHOSPHOCIN DERIVATIVES

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