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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 31, 2001 - Issue 19
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Original Articles

3,7-DICHLORO-2,6-DI-(4,4′-BUTYL-AMIDINO)BENZO[2,1-b:4,5-b′]DITHIO-PHENE DIHYDROCHLORIDE AS POTENTIAL ANTI-HIV AGENT

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Pages 2997-3003 | Received 26 Sep 2000, Published online: 16 Aug 2006
 

Abstract

The multistep synthesis of substituted diamidine of benzodithiophene structure as soluble salt is described. On this way was prepared the compound in title; 3,7-dichloro-2,6-di-(4,4′-n-butyl-amidino)benzo[2,1-b:4,5-b′]dithiophene dihydrochloride 6a. Prepared compound could serve as new intercalator on DNA in the HIV infection.

ACKNOWLEDGMENT

The authors wish to express their gratitude to the Ministry of Science of the Republic of Croatia (scientific project no. 125005) for the financial support of this research.

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