Abstract
A rapid and efficient method for synthesis of α, β-conjugated acetylenic ketones involves reaction of phenylacetylene with aroyl chlorides in the presence of catalytic amount CuI under microwave irradiation to give the corresponding α, β-conjugated acetylenic ketones 3 a–i in 76–93% yields.
ACKNOWLEDGMENTS
We thank the National Natural Science Foundation of China and the Northwest Normal University Science and Technology Development Foundation of China for financial support.