Novel Mercaptopurine and Thioguanine Analogues: The Reaction of Dimethyl N‐Cyanodithioiminocarbonate with Oxo‐ and Amino‐diazoles

Abstract

A novel and efficient method for the synthesis of a new variety of methylsulfanyl derivatives of azoloazines and azoloazoles by the reaction of dimethyl N‐cyanodithioiminocarbonate with diazoles containing oxo‐ and amino functions. The synthetic potential of the method is demonstrated.

Keywords:

• Mercaptopurine
• Thioguanine
• 4‐Aminoantipyrine
• Diazoles
• Dimethyl N‐cyanodithioiminocarbonate
• Azoloazines
• Azoloazoles