Molecular Iodine Catalyzed Highly Rapid Synthesis of 1,5‐Benzodiazepine Derivatives Under Mild Conditions

Abstract

Rapid reaction of o‐phenylenediamines with both cyclic and acyclic ketones in the presence of catalytic amount of iodine afforded 1,5‐benzodiazepine derivatives in excellent yields at room temperature.

Keywords:

• 1,5‐Benzodiazepine
• Molecular iodine
• o‐Phenylenediamine
• Catalyst