One‐Pot Synthesis of Nitriles from Aldehydes and Hydroxylamine Hydrochloride over Silica Gel, Montmorillonites K‐10, and KSF Catalysts in Dry Media Under Microwave Irradiation

Abstract

A rapid and facile one‐pot synthesis of nitriles has been carried out from the corresponding aldehydes and hydroxylamine hydrochloride in the presence of environmentally benign silica gel (84–95%), Mont K‐10 (85–96%), and Mont KSF clay (88–98%) catalysts in dry media under microwave irradiation.

Keywords:

• Nitriles
• Aldehydes
• Hydroxylamine hydrochloride
• Silica gel
• Mont K‐10, Mont KSF

Acknowledgments

We thank Dr. R. Sharma of DayChem Inc. (Dayton) for gifts of Mont K‐10 and KSF clays and Mr. Yashwant for a gift of the microwave oven used in this investigation and Professor A.J. Bellamy for inspiration.