Preparation of Nitrogen Heterocycles of Spiro[Furo[2,3‐d]‐Pyrimidine]Pyrimidine Derivatives

Abstract

The NMR evaluation of the reaction progression of the bromination of heterocyclic dibarbiturates was used to develop an efficient synthetic procedure for the preparation of heterocyclic spiro[furo]pyrimidines. The structure of one of these compounds was confirmed by X‐ray analysis.

Keywords:

• Heterocyclic spiro[furo]pyrimidines
• Pyrimidine derivatives
• X‐ray analysis

Acknowledgment

We would like to thank the Louisiana Board of Regents (LEQSF(2001‐04)‐RD‐B‐12).