Strategies to improve tolerability of rivastigmine: a case series

ABSTRACT

Cholinesterase inhibitors, which act by inhibiting the degradation of acetylcholine in the brain, form the mainstay of therapy for AD. Predominant adverse events are cholinergic in nature, the most frequent being gastrointestinal side effects. Here we present a case series of patients with dementia who were treated with non-standard titration regimens of oral rivastigmine in order to achieve improved tolerability.

Key words: :

• Cholinesterase inhibitor
• Dementia
• Rivastigmine
• Titration
• Tolerability