A double-blind trial of ‘Nethaprin Dospan’ in chronic asthmatic children

Summary

In a study on 36 children with chronic asthma using a randomised double-blind crossover technique comparing ‘Nethaprin Dospan’ against placebo there was considerable improvement in average PEFR and FEV, values in those patients on active medication. These findings were statistically significant at the p < 0.01 level. A sustained broncho-dilator effect way noted over the 9-hour period of assessment. Wheezing, both on normal expiration and on squeezed expiration, was significantly reduced in the treated group (p<0.01). Cardiovascular side-effects encountered in the study- were minimal.

Key words::

• Asthma
• bronchodilator agents
• respiratory function tests
• delayed-action preparations