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Research Article

A double-blind evaluation of ‘Hydergine’ and placebo in the treatment of patients with organic brain syndrome and cerebral arteriosclerosis in a nursing home

, M.D.
Pages 482-487 | Received 19 Sep 1974, Published online: 04 Aug 2008
 

Summary

Forty-eight institutionalised geriatric patients with symptoms attributable to cerebral arteriosclerosis or chronic brain syndrome were studied for 12 weeks on a treatment regimen of either ‘Hydergine’ or placebo according to double-blind design. Patients treated with ‘Hydergine’ experienced greater symptomatic relief than those treated with placebo. Areas of significant improvement with ‘Hydergine’ were restlessness, appearance, initiative, fatigability, sleep difficulties, dizziness, appetite, mobility, irritability, mood, memory, interest in activities, and degree of nursing time. These are areas of importance to the general well-being of the elderly patient in a nursing home. No adverse reaction to treatment occurred.

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