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Current Medical Research and Opinion Volume 4, 1977 - Issue 8
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Research Article

A comparison of nystatin cream with nystatin/triamcinolone acetonide combination cream in the treatment of candidal inflammation of the flexures

G. W. Beveridge Royal Infirmary, Edinburgh, General Hospital, Birmingham, Stobhill General Hospital, Glasgow, Charing Cross Hospital, London; Liverpool Royal Infirmary, and City General Hospital, Stoke-on-Trent, UK
,
E. Fairburn Royal Infirmary, Edinburgh, General Hospital, Birmingham, Stobhill General Hospital, Glasgow, Charing Cross Hospital, London; Liverpool Royal Infirmary, and City General Hospital, Stoke-on-Trent, UK
,
O. A. Finn Royal Infirmary, Edinburgh, General Hospital, Birmingham, Stobhill General Hospital, Glasgow, Charing Cross Hospital, London; Liverpool Royal Infirmary, and City General Hospital, Stoke-on-Trent, UK
,
O. L. S. Scott Royal Infirmary, Edinburgh, General Hospital, Birmingham, Stobhill General Hospital, Glasgow, Charing Cross Hospital, London; Liverpool Royal Infirmary, and City General Hospital, Stoke-on-Trent, UK
,
T. W. Stewart Royal Infirmary, Edinburgh, General Hospital, Birmingham, Stobhill General Hospital, Glasgow, Charing Cross Hospital, London; Liverpool Royal Infirmary, and City General Hospital, Stoke-on-Trent, UK
&
R. Summerly Royal Infirmary, Edinburgh, General Hospital, Birmingham, Stobhill General Hospital, Glasgow, Charing Cross Hospital, London; Liverpool Royal Infirmary, and City General Hospital, Stoke-on-Trent, UK
Pages 584-587 | Received 11 Jan 1977, Published online: 07 Aug 2008
 
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Summary

In a multi-centre double-blind trial, 31 patients with proven bilateral candidal lesions of the flexures were treated for 14 days with nystatin cream on one side and with a combination of nystatin and triamcinolone acetonide cream on the other. Both treatments proved equally effective in terms of mycological cure and clinical improvement. There was a trend in favour of the combination preparation being preferred by both patients and physicians because of more rapid relief of symptoms.

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