The possible mechanisms causing the premenstrual tension syndrome

Summary

The primary cause or causes of premenstrual tension are still uncertain but evidence suggests that endocrine factors play a central role, with changes in prolactin, progesterone and possibly oestradiol being involved. A deficiency of plasma progesterone secretion in the luteal phase is now known to occur in approximately 30 % of premenstrual tension patients. A disturbance of brain amine metabolism, possibly connected with pyridoxine loss, may also be involved. This system may in turn be influenced by the hormonal balance of the patient.

Key Words::

• Premenstrual tension
• hormone balance
• pyridoxine