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Abstract
Background
The present study investigated the effects of a multi-ingredient dietary supplement (MIDS) containing caffeine, conjugated linoleic acid (CLA), green tea, and branched-chain amino acids (BCAA) taken for 8 weeks on body composition, blood lipid profile, glucose, insulin, adiponectin, leptin, and high-sensitivity C-reactive protein (hs-CRP) in overweight and obese men and women.
Methods
Twenty-two participants completed the study (PL, n = 11; 7 women, 4 men; age, 34 ± 3.5 years; height, 169.2 ± 3.3 cm; body mass, 96.9 ± 6.8 kg; BMI, 34.1 ± 1.8 kg/m2; MIDS, n = 11; 9 women, 2 men; age, 36 ± 3.4 years; height, 173.2 ± 2.9 cm; body mass, 91.9 ± 5.6 kg; BMI, 30.0 ± 1.5 kg/m2). Participants were randomly assigned and stratified by body fat percentage to two groups: 1) a soybean oil placebo (PL) or 2) MIDS. Each group consumed two pills with breakfast and two pills with lunch. Body composition and android fat, waist and hip circumferences, blood pressure and heart rate were measured at baseline and after 8 weeks of supplementation.
Results
There were no significant changes for any of the variables of body composition. Feelings of hunger were significantly higher in MIDS versus PL with no changes observed in satiety or desire to eat. Heart rate and blood pressure were unaltered in MIDS after 8 weeks of supplementation. Furthermore, lipid profile, food intake, mood state variables, fasting blood glucose, and endocrine markers did not significantly change regardless of group.
Conclusion
MIDS intake does not appear to alter body composition or markers of cardiovascular health versus PL. Moreover, MIDS may actually increase feelings of hunger versus PL.
Electronic supplementary material
The online version of this article (doi:10.1186/1550-2783-11-37) contains supplementary material, which is available to authorized users.
Electronic supplementary material
The online version of this article (doi:10.1186/1550-2783-11-37) contains supplementary material, which is available to authorized users.
Acknowledgements
This study was supported by a grant from the International Society of Sports Nutrition to MJO. We would like to thank Emery Ward and Wyatt Eddy for their help with data collection. We would also like to thank all of the volunteers for this study.
Competing interests
The authors declare that they have no competing interests.
Authors’ contributions
MJO designed and managed the study, secured funding, analyzed the data and drafted the manuscript. SRR carried out all practical aspects of the study and assisted with data analysis, and manuscript preparation. MTS assisted with study design and manuscript preparation. DAB, AWK, MEE, NF, TAM, and DT assisted data collection and analysis and manuscript preparation. All authors read and approved the final manuscript.