Abstract
A unique case of coincidental splenectomy for trauma during chronic fatigue syndrome (CFS) is presented. The patient had a two-year history of CFS prior to her involvement in a road crash. Delayed rupture of the spleen ten days later necessitated urgent laparotomy. At operation, the splenic parenchyma was spongy and friable. Splenorrhaphy was considered inadvisable and a splenectomy was performed. Histological examination of the spleen revealed chronic inflammatory changes of uncertain etiology. One year post-operatively, the patient recovered from her CFS symptoms and returned to work. These histopathological changes in the spleen of a patient with CFS have not been described before.
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