Recent advances in the development of human rhinovirus 3C protease inhibitors

Abstract

The human rhinoviruses (HRVs) are the most significant cause of the common cold. Important advances in the development of novel, broad spectrum antirhinoviral agents have recently been made by inhibiting the function of virally encoded enzymes essential for viral replication. This article summarises the most recent developments in the design of HRV 3C protease inhibitors which are intended for use as broad spectrum antirhinoviral therapeutic agents.

• 3C protease
• antirhinoviral agents
• human rhinovirus
• protease inhibitors