Recent advances in therapeutic chalcones

Abstract

Naturally-occurring and synthetic chalcone compounds have shown promising biological activity and safety profiles and have the potential to be developed as, or more properly, serve as lead compounds for, the discovery of antioxidant, anti-inflammatory, anticancer or anti-infective agents. Mechanisms of the diverse activities observed with chalcone compounds are not well-defined. This review highlights recent developments and patent activities of chalcones with various therapeutic properties.

• 1,3-diphenyl-2-propen-1-one
• α,β-unsaturated ketone
• antibacterial
• anticancer
• anti-infective
• anti-inflammatory
• antimalarial
• antioxidant
• chalcone