Influence of photodynamic therapy on immunological aspects of disease - an update

Abstract

Photodynamic therapy (PDT) utilises light-absorbing compounds combined with directed photo-irradiation to produce clinical effects. This review updates advances in the understanding of the biochemical pathways triggered by PDT within cells, its influence upon different immune parameters and progress in the use of PDT against human immune-mediated disease. Several works have further defined the notable capacity of PDT to foster anticancer immunity.

• antigen presenting cells
• antitumour immunity
• apoptosis
• autoimmunity
• dendritic cells
• immune modulation
• photodynamic therapy
• psoriasis
• T-lymphocytes