Lamivudine for the treatment of HIV

Abstract

Lamivudine is a nucleoside reverse transcriptase inhibitor that is widely used for the treatment of HIV-1 infection in combination with other antiretrovirals. It is a highly effective agent that can be dosed once or twice daily due to its long intracellular half-life. It also has one of the best tolerability and long-term safety profiles among all antiretroviral agents and continues to be preferred as part of initial or subsequent combination therapy in HIV-infected patients.

Keywords::

• antiretroviral therapy
• HIV
• lamivudine
• nucleoside reverse transcriptase inhibitor