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Abstract
Developing more precise diagnostics approaches to predict cancer progression and prognosis is the key to precision medicine. Overwhelming evidence now suggests that small non-coding RNAs such as miRNAs can be useful tools as biomarkers for molecular diagnostics. miRNAs can serve as biomarkers in a variety of diseases, such as neurological disorders, cardiovascular disease, Type II diabetes, cancer and so on. miRNAs can not only be utilized for monitoring treatment but also for patient stratification and hence are promising predictive biomarkers in cancer progression and prognosis, as well as in predicting drug response. This article focuses on some of the recent findings in the field of miRNA biomarkers and discusses its implications for cancer diagnostics and precision medicine.
Acknowledgements
This editorial discusses recent advancements in miRNA cancer diagnostics field presented at the 2014 microRNA as Biomarkers and Diagnostics conference, Boston, MA, USA. This study was supported by the Intramural Research Program of the Center of Cancer Research, NCI, NIH, and in part by NCI Director’s Innovation Awards in 2009 and 2011 (to PJ Mishra). This is a US government study and is in the public domain of United States of America.
Financial & competing interests disclosure
The author has no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.