Abstract
Unlike traditional clinical trial research, Comparative Effectiveness Research seeks to determine what is ‘best’ for a typical patient when deciding between effective options used in daily practice – a therapy, diagnostic test, or course of action. There is a clear need for Comparative Effectiveness Research in Inflammatory Bowel Disease, a point emphasized by the Institute of Medicine and supported by governmental agencies and escalating funding. This review highlights the rationale and support for Comparative Effectiveness Research, provides examples of Comparative Effectiveness Research in Inflammatory Bowel Disease, and outlines current and future focus for Comparative Effectiveness Research in Inflammatory Bowel Disease.
Financial & competing interest disclosure
M Flasar has received research support from Given Imaging, Inc. and Janssen. R Cross receives consulting fees from/for AbbVie. He participates in advisory boards for Janssen and AbbVie and has research and educational support from Janssen, AbbVie, and UCB. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.