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Abstract
The meeting was held in the beautiful city of Ghent, Belgium, to bring together basic scientists and clinicians working on Escherichia coli and the mucosal immune system; in particular focusing on cellular interactions, immune modulation and vaccination strategies in humans and animals. The aim was to exchange knowledge on the pathogenicity of different types of E. coli and recent advances in the area of mucosal immunity. The meeting was timely given the recent outbreak in northern Germany of an emergent Shiga toxigenic E. coli strain that was associated with the deaths of over 45 people and caused hemolytic uremic syndrome in nearly 800 individuals according to the European Centre for Disease Prevention and Control.
Financial & competing interests disclosure
Both David Gally and Arvind Mahajan have recently entered into a research agreement with Bioniche Animal Health who currently produce an EHEC vaccine with provisional licence approval in Canada. David Gally and Arvind Mahajan also have a patent submission through the University of Edinburgh based on the use of H7 flagellin to generate mucosal responses in cattle. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.