Financial & competing interests disclosure
The author has received conference sponsorship, consultancy fees and lecture fees from Wyeth, Organon (now Merck Sharpe & Dohme) and Schering (now Bayer-Schering). The author has no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.