Abstract
Owing to progress in cancer treatment regimens, cancer survival rates have dramatically improved both in pediatric and reproductive-aged patients. With the expanding availability of fertility preservation methods, a greater number of reproductive-aged and pediatric patients are being invited to utilize one of the various options. Fertility preservation requires an individualized approach. With the increase in success rates of frozen–thawed embryo utilization for IVF, embryo freezing becomes the most widely applied method. Despite the fact that success rates are substantially improved, oocyte freezing is still considered experimental. Other alternative options include in vitro maturation of oocytes and ovarian tissue cryopreservation. In this review, various fertility preservation techniques using cryopreservation technology, gonadotropin-releasing hormone analog cotreatment along with chemotherapy to decrease damage in ovarian reserve, surgical options to preserve fertility and some future techniques are discussed.
Financial & competing interests disclosure
The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.
No writing assistance was utilized in the production of this manuscript.
Notes
†Recent studies demonstrated ovarian compromise with the use of imatinib.
Reproduced with permission from Citation[29].