Financial & competing interests disclosure
Support for this research was provided through grants from the American Heart Association (0920034G to Bradley R Joyce) and the NIH (AI084031 to Ronald C Wek and William J Sullivan Jr and GM49164 to Ronald C Wek). The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.