Global antimicrobial resistance: from surveillance to stewardship. Part 1: surveillance and risk factors for resistance

Abstract

22nd European Congress of Clinical Microbiology and Infectious Diseases

London, UK, 31 March–3 April 2012

As concerns about global antibiotic resistance shift from Gram-positive to Gram-negative bacteria, the annual congress of the European Society of Clinical Microbiology and Infectious Diseases, in London (UK) provided a valuable opportunity for the nearly 10,000 delegates to discuss the latest global trends. In this first report from the conference, the authors review data from the SMART trial, which recently marked a decade of monitoring antibiotic resistance of Gram-negative bacteria from intra-abdominal infections, and from the rapidly developing European Antimicrobial Resistance Surveillance Network. The authors also focus on the spread of nonmetallo-β-lactamase carbapenemases, and likely risk factors for resistance.

Keywords::

• antimicrobial resistance
• extended-spectrum β-lactamase
• Klebsiella pneumoniae carbapenemase
• resistance surveillance
• stewardship

Financial & competing interests disclosure

R Cantón has participated in educational programs sponsored by MSD and AstraZeneca. R Cantón did not receive an honorarium to participate in preparing this manuscript. J Bryan received payment from MSD for attendance at the conference and manuscript preparation. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.

No writing assistance was utilized in the production of this manuscript.