Abstract
Research on spray drying as a processing method to improve vaccine stabilization and to enable novel routes of vaccine delivery has produced promising results; however, the method has yet to be adopted for the manufacture of vaccine products by the pharmaceutical industry. This article reviews the status of spray-drying technology and discusses barriers and opportunities for its future application to vaccines.
Acknowledgements
The authors thank the following individuals for their editorial assistance: Kate Bartholomew, Julian Hickling, Manjari Lal, Patricia Logan, Kristina Lorenson and Amy Wales.
Financial & competing interests disclosure
The development of this article was supported with funds from the Bill & Melinda Gates Foundation through the Thermostable Vaccines for Developing Countries project at PATH. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.
No writing assistance was utilized in the production of this manuscript.