Body Composition and COPD: A New Perspective

Abstract

The proportion of obese or overweight patients in COPD patients is increasing. Although BMI, WC and other easy to measure indicators have been proven to be related to the risk of COPD, they cannot accurately reflect the distribution and changes of body composition, ignoring the body composition (such as fat distribution, muscle content, water content, etc.), the relationship between it and disease risk may be missed. By analyzing the correlation between different body composition indexes and COPD patients, we can provide new research ideas for the prognosis judgment or intervention of COPD disease.

Keywords:

• obesity
• COPD
• body composition
• BMI
• waist circumference
• waist-to-hip ratio
• body fat rate
• visceral fat
• FFMI
• extracellular water
• intracellular water
• phase angle

Abbreviations

COPD, Chronic obstructive pulmonary disease; BMI, body mass index; WC, Waist Circumference; WHR, Waist-to-hip Ratio; WHtR, Waist-to-height Ratio; BFP, Body Fat Percentage; ADPN, circulating adiponectin; SAT, subcutaneous fat; VAT, visceral fat; MetS, metabolic syndrome; FFMI, Fat-free mass index; TNF-α, Tumor necrosis factor –α; ECW, extracellular water; ICW, intracellular water; BIA, bioelectrical impedance analysis; PhA, phase angle; 6 MWD, Six Minute Walk Distance; IL-6, Interleukin 6; IL-8, Interleukin 8.

Acknowledgments

We thank all those who participated in the data collection and revision of the article.

Disclosure

The authors declare that there is no conflict of interests regarding the publication of this paper.

Additional information

Funding

This study is supported by National Natural Science Foundation of China (82060803),Xinjiang Medical University Graduate Innovation and Entrepreneurship Project (CXCY2022027) and Urumqi Science and Technology Talents Project (2019).