Application of Metabolomics in Various Types of Diabetes

Abstract

Metabolomics is the analysis of numerous small molecules known as metabolites. Over the past few years, with the continuous development in metabolomics, it has been widely used in the detection, diagnosis, and treatment of diabetes and has demonstrated great benefits. At the same time, studies on diabetes and its complications have discovered the metabolic markers that are characteristic of diabetes. However, the pathogenesis of diabetes has yet to be clarified, as well as no complete cure. The mechanism of diabetes has not been completely elucidated, and its eradication treatment is not available. Thus, prevention of the onset of the disease and its treatment have become very important. In this review, we focused on the recent progress in the use of metabolites in diabetes and their complications, as well as understanding the impact of diabetes metabolites.

Keywords:

• metabolomics
• diabetes
• diabetes complications
• biomarkers

Acknowledgments

This work was supported by the grants from the China National Natural Science Foundation (81974287).

Disclosure

The authors report no conflicts of interest in this work.