https://orcid.org/0000-0002-6860-0358
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Abstract
Background
In recent decades, obesity has become an epidemic worldwide and is a risk factor for many chronic diseases. Lung function is also a predictor of various chronic diseases. However, research results on the association between obesity and lung function are inconsistent and few studies have evaluated the association between central obesity indicators and lung function. Therefore, this study explored the correlation between central obesity and lung function.
Methods
This study is a cross-sectional study. The basic participant characteristics were collected by questionnaire. A tape measure was used to measure waist circumference (WC) and hip circumference (HC). Body fat percentage was measured using an InBody370. Lung function parameters were measured using a digital spirometer connected to a computer (Chestgraph HI-101). R (R4.0.5) software was used for data analysis. A generalized linear model was used to analyze the association between obesity and lung function.
Results
This study found that body mass index (BMI) adjusted for WC was negatively correlated with forced vital capacity (FVC) (β=−0.05 [−0.06, −0.03] in men, β=−0.05 [−0.07, −0.04] in women) and forced expiratory volume in 1 s (FEV1)(β=−0.02 [−0.03, −0.00] in men, β=−0.03 [−0.04, −0.02] in women). Body fat percentage was negatively correlated with FVC (β=−0.01 [−0.01, −0.01] in men, β=−0.01 [−0.01, −0.00] in women).
Conclusion
Central obesity and combined central and general obesity were more strongly positively correlated with lung function. WC-adjusted BMI was negatively correlated with lung function. Body fat percentage was negatively correlated with lung function.
The Novelty of the Current Study
Most studies on the association between obesity and lung function have been based on obesity as defined by BMI. This study analyzed the relationship between obesity and lung function by combining BMI and some central obesity indices. Most of the research subjects in this area are Caucasians, and there are few studies on Asian races. In this study, obesity and lung function were assessed in a population of the Ningxia Cohort Study from the China Northwest Cohort.
Data Sharing Statement
The datasets used and/or analyzed in the current study are available upon reasonable request from the corresponding authors (Faxuan Wang: [email protected]).
Ethics Approval and Consent to Participate
This study was approved by the Ethics Committee of Ningxia Medical University (No. 2018-012). All participants were provided written and oral information about the study and provided written informed consent before participating in the CNC-NX. And our study complies with the Declaration of Helsinki.
Acknowledgments
We are grateful to all the participants, physical examiners, and data collectors, without whom this study would not have been possible.
Author Contributions
FW, YuhZ, and YiZ designed the study and drafted the manuscript. FW, PH, XT, ZJ, YP, and WH were involved in the data collection. PH, ZJ, and YP conducted the preliminary data collation. PH analyzed the data, wrote the first manuscript draft, and reviewed and edited the manuscript. FW, XT, and WH reviewed the first draft of the manuscript and suggested revisions. FW reviewed and revised the manuscript Finally, all authors have read and approved the manuscript. All authors contributed to data analysis, drafting or revising the article, have agreed on the journal to which the article will be submitted, gave final approval of the version to be published, and agree to be accountable for all aspects of the work.
Disclosure
The authors declare that they have no competing interests.