Gastric neuroendocrine tumors: management and challenges

Abstract:

Gastric neuroendocrine tumors derive from enterochromaffin-like cells in the stomach mucosa. Based on histologic, serologic, and endoscopic findings, they may be further differentiated into types I, II, and III, with varying degrees of aggressiveness. In this article, diagnostic and classification strategies are reviewed, as are endoscopic, systemic, and surgical modalities for management. A multidisciplinary approach is advocated to provide the most effective patient care.

Keywords::

• neuroendocrine
• tumor
• carcinoid
• gastrin
• stomach

Disclosure

EKB has received research funding (to institution) from Novartis and served as a consultant (unpaid) for Ipsen. The other authors report no conflicts of interest in this work.