Orbital plasmablastic lymphoma: a clinico-pathological correlation of a rare disease and review of literature

Abstract

Ocular involvement by plasmablastic lymphoma is extremely rare with very few reports in the literature. Its morphological and immunological resemblance to plasma cell myeloma makes it a diagnostic challenge, while its clinical course, which is characterized by recurrence and death, makes therapy a challenge for clinicians. We present three cases of plasmablastic lymphoma, each of which has distinct clinicoradiological features, and we also review the literature on orbital plasmablastic lymphomas.

Keywords:

• plasmablastic lymphoma
• ocular
• myeloma
• orbit

Acknowledgments

This study has been reviewed by the ethics committee and has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki. Informed consent was obtained from the patients.

Disclosure

The authors report no conflicts of interest in this work.