Beyond Predicting the Number of Infections: Predicting Who is Likely to Be COVID Negative or Positive

Abstract

Background

This study aims to identify individuals’ likelihood of being COVID negative or positive, enabling more targeted infectious disease prevention and control when there is a shortage of COVID-19 testing kits.

Methods

We conducted a primary survey of 521 adults on April 1–10, 2020 in Iran, where 3% reported being COVID-19 positive and 15% were unsure whether they were infected. This relatively high positive rate enabled us to conduct the analysis at the 5% significance level.

Results

Adults who exercised more were more likely to be COVID-19 negative. Each additional hour of exercise per day predicted a 78% increase in the likelihood of being COVID-19 negative. Adults with chronic health issues were 48% more likely to be COVID-19 negative. Those working from home were the most likely to be COVID-19 negative, and those who had stopped working due to the pandemic were the most likely to be COVID-19 positive. Adults employed in larger organizations were less likely to be COVID-19 positive.

Conclusion

This study enables more targeted infectious disease prevention and control by identifying the risk factors of COVID-19 infections from a set of readily accessible information. We hope this research opens a new research avenue to predict the individual likelihood of COVID-19 infection by risk factors.

Keywords:

• individual infection prediction
• COVID-19 infection
• testing shortage
• risk factors

Transparency Declaration

The lead author Stephen X. Zhang affirms that this manuscript is an honest, accurate, and transparent account of the study being reported; that no important aspects of the study have been omitted; and that any discrepancies from the study as planned (and, if relevant, registered) have been explained.

Dissemination Declaration

We plan to disseminate the results to study participants.

Data Sharing Statement

No additional data are available.

Author Contributions

All authors made a significant contribution to the work reported, whether that is in the conception, study design, execution, acquisition of data, analysis and interpretation, or in all these areas; took part in drafting, revising or critically reviewing the article; gave final approval of the version to be published; have agreed on the journal to which the article has been submitted; and agree to be accountable for all aspects of the work.

Disclosure

All authors have completed the ICMJE uniform disclosure form at www.icmje.org/coi_disclosure.pdf and declare: no support from any organization for the submitted work; no financial relationships with any organizations that might have an interest in the submitted work in the previous three years; no other relationships or activities that could appear to have influenced the submitted work.

Additional information

Funding

This research was funded by the MOE Project of Key Research Institute of Humanities and Social Sciences at Universities (16JJD630005).