A database in ACCESS for assessing vaccine serious adverse events

Abstract

Purpose:

To provide a free flexible database for use by any researcher for assessing reports of adverse events after vaccination.

Results:

A database was developed in Microsoft ACCESS to assess reports of serious adverse events after yellow fever vaccination using Brighton Collaboration criteria. The database is partly automated (if data panels contain identical data fields the data are automatically also entered into those fields). The purpose is to provide the database free for developers to add additional panels to assess other vaccines.

Keywords::

• serious adverse events after vaccination
• database
• process to assess vaccine-associated events

Acknowledgments

In 2010 the Global Advisory Committee on Vaccine Safety (GACVS) requested that the World Health Organization (WHO) commission an independent systematic review of the safety of yellow fever vaccine. A systematic review was prepared for the WHO and GACVS by a research team at the University of Calgary headed by Roger E Thomas. The focal contact person for the WHO was Dr Alejandro Costa with Dr Rosamund Lewis. There was extensive correspondence with the WHO focal person and Dr Rosamund Lewis, with additional correspondence with Dr Sergio Yactayo. The literature search for the current article is partly based on the literature search for the commissioned systematic review. The initial literature search and systematic review was funded by The Global Alliance for Vaccines and Immunization (GAVI).

Disclosure

The authors have no conflicts of interest to disclose.